The syndrome of Antiphospholipid is a disorder of the coagulation, which causes clots of blood in arteries and veins, as well as of the complications connected by pregnancy like loss, serious delivery of preterm, or preeclampsia.Antiphospholipid syndrome is also called phospholipid antibody syndrome. Antiphospholipid syndrome can occur in patients without evidence of any definable associated disease or in association with systemic lupus erythematosus or another rheumatic or autoimmune disorder. Certain drugs can cause antiphospholipid antibodies to be produced in the blood, including antibiotics, cocaine, hydralazine, procainamide, and quinine. Nevertheless, the antiphospholipid antibody is not considered a normal blood protein and has been found in patients to be associated with a number of illnesses. In pregnancy, the placenta can be affected by small clots, and there is an increased risk of miscarriage, particularly in mid-pregnancy.

Antiphospholipid antibodies can be found also in the blood of individuals without some sickness process. The patients with the antiphospholipid can syndrome a mixture have of antibodies to molecules phospholipids called in their blood. Antiphosphilipid syndrome can cause many other problems. In antiphospholipid syndrome patients, the most common venous event is deep vein thrombosis of the lower extremities and the most common arterial event is stroke. Patients with antiphospholipid syndrome have developed abnormal symptoms while having antiphospholipid antibodies that are detectable with blood testing. When only the symptoms of the antiphospholipid syndrome occur, this is known as primary antiphospholipid syndrome. The secondary form occurs in association with another autoimmune disease, usually systemic lupus erythematosus. Both types are more common in women.

Certain people develop the red measles to have the lace with, winds style in theirs wrist and knee. Clots may also occur in the lung, sometimes following a clot in the leg, which breaks off and travels in the circulation until it lodges in part of the blood supply to the lung. Some clots occur in patients soon after starting on the oral contraceptive pill. Such arterial diseases occur commonly from atherosclerosis in old age, but in the antiphospholipid syndrome they can happen at a much younger age. Some patients may present with recurrent pregnancy losses often, but not always, in late second or third trimester of gestation. Both preeclampsia and intrauterine growth retardation have been observed concomitantly. Patients who present a history of previous pregnancy loss are subject to a new event more frequently. Some people experience a decrease in platelets, blood cells necessary for normal clotting.

Most often, Antiphospholipid syndrome is detected after a thrombotic event or recurrent miscarriages. Because many of the features of illness with anticardiolipin syndrome are associated with an abnormal grouping of normal blood clotting elements, treatment is often directed toward preventing clotting by thinning the blood. Patients with this disorder have an abnormal tendency to form blood clots. Often, this disease is treated by giving aspirin to inhibit platelet activation, and warfarin as an anticoagulant. Medications that thin the blood, such as heparin and warfarin, are used for treatment. Aspirin has an affect on platelets that inhibits their grouping and has also been used in low doses to thin the blood of selected patients. Other treatments include the use of intravenous gamma globulin for selected patients with histories of premature miscarriage and those with low blood-clotting elements during pregnancy.


5 thoughts on “Complete Information On Antiphospholipid Syndrome With Treatment And Prevention

  1. cortlin.harrison

    is this a good research project please be honest?
    Cortlin Harrison Science 10-12
    Mrs. Cooney/ Mrs. Barends ELA 21-23
    May 19, 2009
    Antiphospholipid Syndrome

    Antiphospholipid Syndrome is a disorder in which the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies against them. This disorder is non-infectious which means that this disorder can’t be passed from person to person by contact. Pregnant women are more prone to get this disorder than anyone else, and African Americans, and Hispanics but like other disorders anyone can get Antiphospholipid Syndrome

    The symptoms and characteristics of this disorder are not hard to spot. Some symptoms of the disorder are veins or arteries of the arms or legs may cause pain, numbness, tingling in the feet. Arteries of the heart may cause chest pain or heart attack, the individual with this disorder may have heart murmur. In pregnant women with Antiphospholipid Syndrome, miscarriage can occur prior to 20 week of gestation, while pre-eclampsia is reported to occur after that time. Blood vessels of the skin – may cause painful bruises (purpura) or a condition called livedo reticularis. Blood vessels of the brain – if a clot cuts off blood supply to a part of the brain, this causes a stroke. An individual with APS may also experience migraine headaches or seizures.

    There is no cure and there is no way to avoid getting this disorder. There are many treatments for this disorder. But the most successful treatment is anticoagulant therapy. This is usually successful in preventing further blood clots. This disorder can severely damage the body in many different ways because good cells attack other good cells and that causes chaos through the body. And when a weak or strong pathogen enters the body it can be deadly.

    Some other information about Antiphospholipid Syndrome is, 1-5% of the world population is known to have this disorder, and 40-50% of patients with lupus also have APS. One third of strokes occurring in younger people (under the age of 50) are due to Antiphospholipid Syndrome. One third of patients with Antiphospholipid Syndrome are said to have lupus, and or Raynaud disease. APS is more common in young to middle-aged adults; however, it also manifests in children and elderly people. Disease onset has been reported in children as young as 8 months.

    This disorder is very rare and not very deadly but this disorder can still affect your way of life, the way you think, and can make you dizzy and other things. My mom has this disorder and sometimes it’s hard to get around and such, but you can still fight back by eating a healthy diet and seeing a special doctor called a Rheumatologist, this doctor specializes in these types of rare disorders.

  2. baby m @ home

    I would like to know if anyone out there has been on Coumadin/Lovenox therapy for treatment of a mild stroke?
    I was 6 weeks post-partum when I found out after having a stroke that I have a blood disorder in which the antibodies in the blood tend to clot my blood (Lupus-anticoagulant). I have been on Coumadin/Lovenox therapy for 1 1/2 months now and cannot reach a recommended PT/INR level between 2 and 3. Until my weekly pricks to check these levels is at this number, I must continue the Lovenox injections as a safety precaution because the Coumadin is not working well. I am now taking 12.5 mg ( I was on 10mg) a day. I guess you can say I’m frustrated because when I initially started this therapy I was told that I should be at the recommended level in about a week . Now at 1 1/2 months later I feel like a guinea pig trying a high dose(not helping) so now a higher dose (let’s see how your body accepts it at this dose). I’ve kept up with the diet guidelines and really feel this is not the problem.

    If anyone knows about what I’m talking about please respond.

  3. MEM

    I had an ultrasound scan & it showed 5cm submucosal fibroid. What treatment options do I have?
    I also have Factor V Leiden & Lupus anticoagulant. Due to these, ANY kind of hormone therapy is not allowed. I’m 32 and have no children. I would like to be able to have them if I can (someday). My Dr says to “wait & see”. Anemia, pelvic pain, pressure, heavy bleeding & large clots are unbearable & I’m confined to bed for 24-48 hours of my period. I only have symptoms during my period, the rest of the month – I am fine. Pain has persisted for at least 8 months.
    cannot take Lupron, it is a hormone. Factor V Leiden patients cannot take hormones due to the increased risk of blood clots.

    1. BSB_Baby_Love

      Have you tried asking if you are a candidate for a myomectomy? A myomectomy is a surgery to remove just the fibroid itself. As a note, if they actually have to cut into the cavity of your uterus during the surgery, you will not be able to deliver any future babies vaginally. So as long as you can live with having a C-Section when you have a baby, this could be an option for you.

      If surgery is not an option, you could try a drug called Lupron, which sometimes is useful for shrinking the fibroid and relieving your symptoms.

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