Overcome Infertility 108--Treating Anti-phospholipid antibody Syndrome In Conventional Perspective
Author: Kyle J. Norton
As we mentioned in previous article, conventional medicine plays an important role and most of the time is the first treatment for a couple who for what ever reason cam not conceive after 1 year of unprotected sexual intercourse or can not carry the pregnancy to full term. Immune system plays an important role in protect our body against forming of free radicals and bacteria and virus, but for what ever reasons, sometime the immune system attack sperm in the women reproductive organs or sperm in the testes in men, leading to infertility In this article, we will discuss how anti-phospholipid
1. Definition
Anti phospholipid antibody is lupuslike syndrome and defined as a condition of which causes blood clotting in the arteries or veins including Lupus anticoagulant and anticardiolopin antibody. Some women may have anti phospholipid antibody but does show any symptom of immune antibody disorder.
2. How anti-phospholipid antibody syndrome affects fertility
a) Nutrient deficiency
As the syndrome progress, it causes blood thicken that interferes with function of blood in transportation nutrients to ovaries and uterine lining, making difficult for fertility and causing miscarriage.
b) Placenta
Some researchers believe that anti-phospholipid antibody may causes microscopic blood clot in
the blood vessels in the placenta, leading to miscarriage and poor fetus growth.
c) Recurrent pregnancy loss
Study show that women who have anti-phospholipid antibody syndrome and sufer loss of pregnancy will like to sufer again, if pregnancy does occur.
3. Treatment
a) Heparin
Heparin is a member of anticoagulants, it helps to prevent the formation of blood clots in the blood vessels, thereby increasing the blood in transportation of nutrients to the reproductive organs leading to high chance of fertility and lessening the risk of pregnancy loss. Heparin can be injected through the skin or given into a vein by intravenous infusion.
b) Prednisone
Prednisone is defined as a member of drugs called steroids, it is normally used to prevent the release of substances in the body that cause inflammation. It also has an ability to reduce the function of anticardiolipin antibodies and the lupus anticoagulant, thereby, lessening the risk of blood clot and increasing the chance of fertility.
c) Low of asprin
Sometime low dose of aspirin may be added to prenisone or heparin to increase the function of the medication in preventing blood clot, but aspirin is unlikely to be used alone as a medication in anticoagulation.
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Tags: causes of infertility, fertility, infertility, infertility treatment, lupus, lupus anticoagulant syndrome, pregnancy, types of infertility
The difference between APS and Lupus?
So if someone has the Lupus Anticoagulant antibody is that one of the ANA’s that is needed to be diagnosed with Lupus? I have been diagnosed with Antiphosolipid Antibody Syndrome because of the antibody, the multiple miscarriages, TIA’s and clotting etc. However, I also have many many symptoms of Lupus are the terms interchangable?
I would think so.
I was told by a doctor that I had Lupus but upon checking into it further cuz I certainly was not going to let that one go, so I checked with another doctor, he said that my ANA showed it was positive for Lupus but my level was not indicitive of a level that I had to worry about, he said, most everyone will show a positive for that ANA factor/level to some degree, however it’s termed. But that doesn’t mean I actually have Lupus, apparently the first doctor that told me that, had no clue what level the ANA should show to diagnose someone like that, he scared me.
What to expect with a diagnosis of Purpura Fulmicans and Lupus Anticoagulant w/possible Phophosilid syndrome?
My 20 month old daughter was recently diagnosed with this in a Children’s Hospital she was sent to. I’ve looked on line, but I can’t find anything on living with it, life expectancy, or any preventative measures to take. All I can find is some descriptions and a few pictures. I know it’s rare, but surely someone can give me some advice.
Thanks.
God, I’m so sorry about the diagnosis. Purpura Fulmicans is usually associated with some underlying infection such as meningitis. It can decrease the blood flow/pressure, sometimes causing digits to be amputated. The Lupus Anticoagulant/Antiphospholipid Syndrome is a clotting disease that can be treated with blood thinners/aspirin. Blood clots are common in people with APS and early onset usually implies greater complications.
The primary issue is finding the underlying cause of the Purpura Fulmicans and treating it. Usually this will subside after the cause is treated. APS is a different story and is a lifelong issue. There is a much higher rate of heart attack and stroke in people with APS, however, with vigilant treatment lifespan can be normal.
My wife has APS and Lupus and is doing just fine. She has had two blood clots and a heart attack but survived them all because we knew what was going on.
False positive drug test?
Ok I needed some good educated answers here. I was taking sudafed the regular kind not the new sudafed pe but the kind you have to get behind the counter you know with the pseudoephedrine in it back in March. I was admitted to the hospital because I had 2 mini strokes aka T.I.A.’s. My drug screen came up positive for amphetimines and no one believes me that all I was taking was sudafed. I’ve looked it up on many sites and about 80% of them say yes sudafed can cause a false positive in a urine drug screen which is what they did. Pseudoephedrine is the main ingredient meth makers use to make meth so I don’t see why it wouldn’t show up positive. Since That march I have had 1 more mini stroke and 1 major stroke and tested clean for amphetamines shouldn’t everyone believe me now? My blood tests are showing positive for Lupus Anticoagulant also. They call this Anti Phosholipid Syndrome or APS. I’m just really struggling with this because my wife will not let me live it down! I hate tweekers, never have been one and never will be one. Can someone do some research into this and give me links saying sudafed can give false positives. Thanks.
In urine tests, pseudoephedrine CAN trigger a false positive in a drug test. There is a list of false positives for amphetamines listed on Erowid.
is this a good research project please be honest?
Cortlin Harrison Science 10-12
Mrs. Cooney/ Mrs. Barends ELA 21-23
May 19, 2009
Antiphospholipid Syndrome
Antiphospholipid Syndrome is a disorder in which the body recognizes certain normal components of blood and/or cell membranes as foreign substances and produces antibodies against them. This disorder is non-infectious which means that this disorder can’t be passed from person to person by contact. Pregnant women are more prone to get this disorder than anyone else, and African Americans, and Hispanics but like other disorders anyone can get Antiphospholipid Syndrome
The symptoms and characteristics of this disorder are not hard to spot. Some symptoms of the disorder are veins or arteries of the arms or legs may cause pain, numbness, tingling in the feet. Arteries of the heart may cause chest pain or heart attack, the individual with this disorder may have heart murmur. In pregnant women with Antiphospholipid Syndrome, miscarriage can occur prior to 20 week of gestation, while pre-eclampsia is reported to occur after that time. Blood vessels of the skin – may cause painful bruises (purpura) or a condition called livedo reticularis. Blood vessels of the brain – if a clot cuts off blood supply to a part of the brain, this causes a stroke. An individual with APS may also experience migraine headaches or seizures.
There is no cure and there is no way to avoid getting this disorder. There are many treatments for this disorder. But the most successful treatment is anticoagulant therapy. This is usually successful in preventing further blood clots. This disorder can severely damage the body in many different ways because good cells attack other good cells and that causes chaos through the body. And when a weak or strong pathogen enters the body it can be deadly.
Some other information about Antiphospholipid Syndrome is, 1-5% of the world population is known to have this disorder, and 40-50% of patients with lupus also have APS. One third of strokes occurring in younger people (under the age of 50) are due to Antiphospholipid Syndrome. One third of patients with Antiphospholipid Syndrome are said to have lupus, and or Raynaud disease. APS is more common in young to middle-aged adults; however, it also manifests in children and elderly people. Disease onset has been reported in children as young as 8 months.
This disorder is very rare and not very deadly but this disorder can still affect your way of life, the way you think, and can make you dizzy and other things. My mom has this disorder and sometimes it’s hard to get around and such, but you can still fight back by eating a healthy diet and seeing a special doctor called a Rheumatologist, this doctor specializes in these types of rare disorders.
very cool research project!
Especially when someone yu kno very well has it…
I have lost two pregnancies. What shall I do?
Hello!
I am 25 years old. In February 2009 i had a miscarriage, i was about 8-9 weeks pregnant. The size of the embryo was 19mm.
After that, a month later(until 13.04.09) I Took the following test with results:
1) Immune status:
Anticardiolipin IgG -11,5 (lab norm 10)
Anticardiolipin IgM -37.2 (lab norm 10)
Antiphospholipid IgG -3.7 (lab norm 10)
Antiphospholipid IgM -8.8 (lab norm 10)
2) Analysis of hemostasis results were good
3) anti-CMV IgG (Cytomegalovirus) -7.5 (lab norms 0-0,5)
anti-CMV IgM -negative (norm – negative)
anti-T gondii IgG (Toxoplasma) -103.1 (norms 0-50)
anti-T godnii IgM (Toxoplasma) negative (norm – negative)
anti-HSV, type 1,2 IgG (herpes) -121.6 (norms 0-5.0)
anti-HSV, type 1,2 IgM (herpes) – negative (norm – negative)
5) Mycoplasmosis, ureoplasmosis – negative
6) Testosterone , prolactin, LH, FSH, T-4, TSH – normal
7) Antibody to rubella – negative
My doctor on thought it might be antiphospholipid syndrome.
7 months later, in September, we have decided to try to conceive again.
Ultrasound (12 October) – uterine pregnancy, the size of fetal egg 0,5 cm
Ultrasound (10 November) – the size of fetal egg 2,5 cm, CTE -0,9 ,detected heartbeat
Ultrasound (22 November) – an embryo is not visualized, the size of fetal egg 2,4 cm
Around week 6-7 the baby stopped developing (supposed to be 9 weeks)
23 November – surgical abortion, antibiotics.
During the pregnancy i did the following tests:
October 20
1) Anticardiolipin IgG: 18,0 (norm 0-48)
Anticardiolipin IgM: 17,2 (norm 0-44)
October 13
2) Lupus Anticoagulant – negative
November 12
Lupus Anticoagulant – negative
3) Progesterone-normal
4) DHEA -3,0 (norm 0,9-3,6)
Tests results after clinical abortion:
November 26
anti-CMV IgG (CMV)-positive
anti-CMV IgM (CMV)-negative
anti-HSV, type 1,2 IgG (herpes) – positive
anti-HSV, type 1,2 IgM (herpes) – negative
If you could please advise me what i could do or what other tests there’re to run?
What could be the reason of my pregnancies termination?
Thanks you a lot in advance
Looking forward to your response.
Sincerely, Natalia
I had 2 doctors during my pregnancies,but one doctor refused to deal with my problem. Another doctor said, that my analysies are good and she saw no reason why miscarriages. On the beginning of the month I will go to genetics
Hi Natalia! I don’t intend on reading this long chart, that’s not what I come here for. Ask a live doctor what the reason is, not strangers on Yahoo Answers. I am sorry that you have herpes.
Sincerely, Hi Omg Omg Hi