How to Tackle Lupus Disease

Author: Davis Seme

As a result and consequently, this condition act against the bodies own tissues, causing inflammation. When these autoimmunes act against the own body tissues, they are so therefore referred to as autoantibodies.

The National Institute of health sciences put that Afro (black women) are more at risk of contracting the disease than their white counterparts. This notion comes from the recorded number of cases involving the blacks to be higher than that of whites. It also intimates that black women tend to develop the disease at a younger age. Complications that are more serious manifest are accorded statistically nine times more in women than in men.

Forms

One of its many forms is defined in X-linked form of the disease as a carrier type. Carrier types are those do not show outright disease symptoms but well patched in the human Body. In general, carrier mothers are healthy, only their progeny may have lupus. However, in some cases carriers may get recurrent mouth ulcers or even regular skin infections especially when exposed to the sun.

Some people find that they have problems with their hands in the cold with their skin becoming very white or blue colored.

Only occasionally, these mothers may have symptoms associated with lupus disease. In these carriers, lupus-like symptoms such as tiredness, skin rashes and joint pains can be diagnosed through blood test, although studies have shown either negative blood tests or only weakly positive blood tests.

There are two forms of the disease: discoid lupus erythematosus (or DLE) is largely confined to the skin. The second form of this condition, systemic lupus erythematosus (SLE) is more generalized. The systemic form of lupus can be a more unpredictable condition, which should be carefully monitored by a Rheumatologist (often in a special ‘lupus clinic’).

 

Manifestations and how to know if you have lupus

Blood tests are applied to verify into types of autoantibodies (anti nuclear antibodies (ANA), and antibodies to double stranded DNA (which makes up genes and chromosomes) which indicate the most vulnerable parts of the body.

Lupus attacks many parts of the body, including the joints, skin, kidneys, heart, lungs, blood vessels, and brain molecular changes occur in the brains of people with lupus.

The antibodies that attack the DNA of people with lupus can also attack molecules that bind a particular neurotransmitter (glutamate) involved in nerve cell activity

Cure

While current lupus treatments work by suppressing the entire immune system, treatments such as rituximab selectively targets the subset of white blood cells, called B-lymphocytes that are at the root of the problem in lupus. People who have more serious complications associated with systemic lupus may be treated with steroid tablets or other drugs, which damp down the immune system (immunosuppressant medication). People on these medications need to be carefully monitored and have regular blood tests and consult their doctors.

Today

Many people today can be diagnosed conclusively. There is hope for a significantly increased life span and improved quality of life. A number of genes associated with lupus risk and its severity have been discovered. Some  of these are linked in patient populations at high risk of having lupus.

 

Basic study on animal models of lupus has documented the novel, targeted, and relatively less toxic therapy of utilizing short peptides (protein fragments) preceding  the development of symptoms of lupus that has resulted in slowed onset of lupus kidney disease as well as prolonged survival and halting of the progression of kidney disease in those who already have lupus.

 

Most lupus related studies have proposed an array of steps that can be taken to deal with the disease.

In the future, identifying lupus patients at particular risk for severe disease before serious complications arise has implications for early diagnosis and treatment. Therefore, this calls for further research. Genetic studies that would allow the identification of those at risk for lupus so that interventions can be made earlier in the disease process will be very useful.

 

Today, the variations in disease, course and severity that are associated with women and people in minority populations can be eliminated if our understanding of health disparities is improved, and treatments can be targeted to all affected individuals in a personalized way. In addition, some people with lupus have kidney disease, while some have predominantly central nervous system disease. In the future, there will necessitate having therapies designed for specific problem of lupus patients.

 

Identification of lupus as well as chances limiting one’s susceptibility to the disease will allow preemptive strategies to be developed. Because antibodies in the blood precede diagnosis of lupus by many years, it will be important for instance if the ongoing prevention trial of lupus in children will become available. Equally therapies that preemptively shield the binding of antibodies to kidneys and brain thereby block the injury to organ targets that lupus causes

 

Article Source: http://www.articlesbase.com/womens-health-articles/how-to-tackle-lupus-disease-2302428.html

About the Author

An IT and Health Writer


Lupus Bible

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9 Comments on Lupus In Children

  1. akjras says:

    how does lupus affect children in Western New york, where can i get info on it?

  2. Show says:

    prognosis for children with lupus?
    My 8 year old cousin was diagnosed with lupus when he was 4 or 5. He’s had rashes, is sensitive to the sun, and fevers since he was a baby. He’s also been on many different kinds of medication, including steroids. Recently, he had blood in his urine, which means that it’s affecting his kidneys. I was hoping someone could tell me the possibility of him dying at a young age, or if anyone had any personal experiences [even if you were diagnosed at a later age or have a less severe case of it] that could elaborate on that.

    Please don’t post paragraphs from websites of medical bull that I can’t understand, thanks. I’ve probably already read it anyway.
    Thanks for your input. I can assure you that I don’t treat him any differently than other children, either!
    I still am hoping for other experiences, so please keep posting. I’m just curious about how people cope with it.

    • mgunnycappo says:

      My daughter was just diagnosed with Lupus and my wife has had severe organ involved Lupus since she was 15. Unfortunately they younger you are when you’re diagnosed the poor the prognosis is. This is because in order to be diagnosed with Lupus you must be exhibiting symptoms. Lupus is a progressive disease and usually gets worse with age because you have more flares over time which cause more and more damage. So when you’re diagnosed so young this means that your organs have been exposed to more flares throughout your lifetime.

      The good news is that more and more medications are being tested every day meaning that the possibility of a cure could be only a few years away or at least a medication that is better at treating Lupus than those that are already on the market.

      Also, a lot more is known about Lupus now then it was when my wife was diagnosed. I know that for our daughter the future is looking better each and every day.

      We run a Lupus Support Group to help us cope. Dealing with others who have problems helps us give back and also lets us meet people like us. If you have the opportunity to go to a support group meeting I would highly suggest doing so.

      Good luck to you and your family.

  3. marpad2004 says:

    I have lupus. Is lupus heriditery, and should i have my children checked?
    I’ve been diagnosed with SLE lupus since february of 2003. Prior my diagnosis. I was told all my symptoms were in my head and was told i was a nut case. I also have endometriosis. I have a daughter who is starting now the same path with her health as I have with mine. I concerned she my have lupus. I would like to know what her chances are, if any, if she test positive.

    • Dr. Ima G. Neus says:

      My sister is a carrier but does not exhibit any of the symptoms. She found out when she went through in-vitro pregnancy. She had to have the boys tested after they were born.

  4. Why? says:

    Are you a Jehovah’s Witness Child Living With Lupus Or Similar Health Condition?
    Our daughter is a Publisher and we are Witnesses of our God Jehovah. We are looking for other children in the faith who have Lupus or a similar condition to connect with for fellowship and friendship and support. It is hard at age 11 years old to keep up with friends who are healthy and active. It would be nice for our daughter to find another child to relate to in the faith.

    • mgunnycappo says:

      I hope that you are seeking medical attention for your child. As much as I am in favor of people being able to practice their own religion…that stops short of abusing your child by denying medical attention. Lupus can be a manageable disease if treated, however can be life threatening if left untreated.

      Case law prohibits you from denying your child medical attention if they require it. I hope this is not the case.

      Good luck to you.

  5. beautifullyundone says:

    Lupus and having Children?
    I just found out that I have Lupus. Its not at a bad stage right now and I know throughout life I will have good days and bad days. My delima now is, should I think about having kids in the future? I would love to have kids, but what if I have Lupus really bad when I get older? It wouldn’t be fair to my kids if I wasnt able to take care of them all the time. I would feel like I was neglecting them. If you knew you had Lupus, how would if effect your decision on having children?

    • mgunnycappo says:

      A very important factor in your decison to have children is if you have APS or Antiphospholipid Syndrome. This is a secondary disease found in about 50% of Lupus patients. This disease causes blood clots to form and is believed to cause many of the miscarriages that are associated with Lupus. If you do have APS then you may be wise to seek alternative methods to having children, ie adoption, surrogacy..etc. Without APS a person with Lupus can have a fairly normal pregnancy. Of course it will be considered ‘high risk’ and you’ll have to be closely monitored. Additionally, almost no babies born to Lupus patients are full term. It is also important to plan your pregnancy around your flares. An unplanned pregnancy during a Lupus flare could be terrible as many of the medications used to quell a flare are very damaging to the baby.

      You should be tested for APS immediately, regardless of if you have children or not because left untreated you are at an extremely high risk for DVT, PE, Stroke and Heart Attack. Then I would discuss your desire to have children with a high risk OBGYN who has delivered babies to women with Lupus. This will give you the most realistic outlook on your options.

      I wish you the best of Luck!

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