Glomerulonephritis is a type of kidney disease Glomerulonephritis is a disease that involves inflammation of the glomeruli a€” the filtering units of the kidneys. This inflammation and subsequent damage to the glomeruli affects their ability to filter waste products and excess water from the blood. Glomerulonephritis may be either acute, with a sudden onset of inflammation, or chronic, involving persistent inflammation that comes on more gradually. Many people with glomerulonephritis have no symptoms. When symptoms occur, they are often flu-like, such as general fatigue, nausea, vomiting, loss of appetite, fever, and abdominal and joint pain.

These types of general symptoms can continue for up to one month before symptoms of kidney failure appear. Patients whose kidneys are failing will produce only small amounts of urine and have swelling (edema) from fluid build-up. Symptoms of acute glomerulonephritis usually occur around two to three weeks after a streptococcal infection and begin with swelling. They can progress to high blood pressure, visual disturbances, shortness of breath, blood in the urine, and a reduction in urine production.Glomerular disease can be part of a systemic disease, such as lupus or diabetes, or it can be a disease by itself primary glomerulonephritis.

There are several types of glomerulonephritis; some are more serious and long-term than others. Glomerulonephritis often follows an infection such as an infection of the throat (pharyngitis). Glomerulonephritis can be caused by various disorders, such as infections, an inherited genetic disorder, or autoimmune disorders. Glomerulonephritis can be a complication of streptococcal infections, including strep throat, particularly in children ages 6 to 10. Less often, it results from other bacterial or viral infections, especially measles, mumps, mononucleosis and human immunodeficiency virus (HIV).

Other causes include some problems with the immune system (especially those involving immunoglobulin A antibodies), systemic lupus erythematosus (also called SLE or lupus), and inflammation of the kidney’s blood vessels (vasculitis). Glomerulonephritis can develop over a short time period (acute glomerulonephritis) or develop and progress slowly (chronic glomerulonephritis). Treatment varies depending on the cause of the disorder, and the type and severity of symptoms. High blood pressure may be difficult to control, and it is generally the most important aspect of treatment.

If a bacterial infection is still present when acute glomerulonephritis is discovered, antibiotic therapy is started. Antimalarial drugs may be beneficial if the cause of the syndrome is malaria. Various antihypertensive medications may be used to attempt to control high blood pressure. Corticosteroids, immunosuppressives, or other medications may be used to treat some of the causes of chronic glomerulonephritis. There is no specific prevention of glomerulonephritis. Some cases may be prevented by avoiding or limiting exposure to organic solvents, mercury, and nonsteroidal anti-inflammatory analgesics.

5 thoughts on “Symptoms Of Lupus Nephritis

  1. Qb

    What are the risks of nephritis?
    One of my friends has been having trouble with what seems to be her kidneys for almost a year now. She’s just gotten a biopsy, and is waiting on results.

    Her doctor believes she has nephritis, because she has every symptom associated with it.

    I’m clearly not an expert on the disease of nephritis, or Lupus nephritis, but can either be deadly?

    Because this has been going on so long, is there a high possibility of her needing to get either a transplant, or go on permanent dialysis, or could she even die from it at this stage?

  2. monica7s

    Nephritis and Lupus?
    I have a son who was originally diagnosed with Nephritis. Now he has been diagnosed with Lupus also. Just wondering if there are any other parents out there with a similar situation. He is 14 and used to be very athletic before all of his symptoms hit.
    I need to add that he is being seen by a very well known nephrologist at the University hospital of Missouri in Columbia. He actually sees 4 different specialists there. The nephrologist, rheumatologist, endocrynologist and dermatologist. He sees his nephrologist and rhuemtologist every 6 weeks. The others about every 3 months. I would very much like to find him a support group with children close to his age. Thank you all for your replies thus far.

  3. sondra w

    i have lupus and horrible doctors how can i get a good doc to treat my symptoms seriuously?
    i suffered w/ chronic pain for a year before i was admittedin the hospital and finally dignosed its been five yrs now and class 3 nephritis w/good kidney function, i take 10 mg of predisone, 150mg of imuran and 400mg of plaqunil, also i take 8, 40 mg of oxycotin, i just want to stop living in pain, and have another child, when i talk to the doctors they act like theres nothing wrong, but tell me i should never try to have a child again, what can i do to get the help i need and stop this diesease?

    1. Julia B

      Lupus can’t be cured and you definitely can’t stop the disease process… Some have worse symptoms than others, but my mom was diagnosed 5 years after I was born, but started getting symptoms once I was born… They don’t know what causes it exactly, but something about childbirth tends to “set it off”…You can have another child, my mom had my sister 6 years afterwards, but she “acquired” more symptoms… Be careful with prednisone my mom took it for years—it’s a miracle short term drug but when taken long term like my mom did will deteriorate your bones—I’m not trying to scare you but my mom isn’t even 40 and has 2 prostetic hips—she’s had it for almost 20 years and looking at her you can’t tell there’s anything “wrong” til you watch her… The pain will be bearable some days and not so bearable on others… Weather has an effect on it as well especially if you have arthritis… The best thing you can do for your child is be strong… The disease is an autoimmune disease which affects everything in your life… from sun exposure (can’t have too much or you can get a butterfly rash and or lesions) to feeling like you don’t want to do anything whatsoever… Finding a good doc is difficult especially cause most have either just heard of lupus or know little to nothing about it… I do feel for you and hope the best with you and your child and hopefully another in the future…

  4. Yannie

    Protein and blood in urine & Lupus?
    I already know I have grade 4 lupus nephritis (glomerulornephritis) , but today I did a urine dipstick test myself ( I am a student Nurse) and I the results said * BLO LARGE * and *PRO >=300mg/dl*. I also have been experiencing backache near my kidneys. What should I do? I do not have any symptoms of a lupus flare but I am really worried as I have had acute renal failure because of my lupus before and I really really don’t want to go through that again. Could it be because of the small amount of permanent damage they said I had last time, or is this still abnormal?

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