The causes of hair loss are numerous.

Diffuse hair loss: androgenetic alopecia, telogen effluvium, anagen effluvium, alopecia areata
Among the diffuse hair loss, the most common are the common hair loss (androgenic alopecia male and female) and telogen effluvium (after a high fever, pregnancy, drug taking or a strict diet). The anagen effluvium in turn causes a sudden loss of hair after chemotherapy or during alopecia areata. The genetic hair loss occur at birth or rather during childhood (moniletrix syndrome of anagen hair, ectodermal dysplasia).

Localized hair loss: androgenetic alopecia, alopecia areata, cicatricial alopecia, tumors
The localized hair loss occur in the context of male androgenic alopecia (gulfs, tonsure), fungal infections (ringworm), alopecia areata in plaques, alopecia induced by pulling (trichotillomania, braids and hair straightening) or cicatricial alopecia (lupus erythematosus, lichen, folliculitis decalvans, central centrifugal scarring alopecia, frontal fibrosing alopecia in postmenopausal …). Tumors and skin growths are also accompanied by hair loss localized (sebaceous nevus, basal cell carcinoma, squamous cell carcinoma).

Stress and hair loss
Responsibility stress has often been implicated in the onset of hair loss but has not hitherto been confirmed by scientific studies. However, we are all victims of stress induced by the events of everyday life, we must consider the role of stress when hair loss occurs in significant weeks of emotion intensity abnormally high.

Treatment of hair loss
Effective treatment of hair loss needs to determine the cause.

The telogen effluvium may indicate support for a deficiency (iron, vitamin B12) or a thyroid problem but they usually heal without treatment after 3 to 4 months (after pregnancy, fever, surgery, ect …). The telogen effluvium induced by taking medication (isotretinoin, cholesterol, blood thinner …) where possible require replacement therapy with another molecule.

The anagen effluvium chemotherapy may, to some extent be minimized by preventive measures (cooling helmet).

The skin and systemic conditions that cause hair loss should receive specific treatment tailored to each case. Ringworm requires antifungal therapy systemically. Treatment of lichen uses topical steroids, intralesional or general and sometimes synthetic antimalarials (Plaquenil). The cicatricial alopecia treatment are difficult, they require the use of an expert from the scalp. Once the reconstruction process stabilized by hair transplant is sometimes possible.

The Congenital alopecia may sometimes benefit from hair restoration through hair transplants or hair supplements.

Alopecia areata in small plates often heal quickly without treatment but may recur while alopecia most important involve rapid response that involves the topical steroids (lotion), intralesional (injections into the scalp) or rarely in the corticosteroid General. PUVA, the dioxyanthranol and application of a sensitizing substance (diphencyprone) treatments are often recommended.

The male androgenic alopecia benefits of treatment with finasteride (Propecia ) and minoxidil 5%, dutasteride has demonstrated its superiority over finasteride in a large U.S. study, it has not yet authorized release on market in this indication. When the hair has completely disappeared from an area, hair transplants are the only way to “Most natural hair. Current techniques of follicular grafts yield excellent results when performed by expert teams.

The female androgenic alopecia is a common treatment is called minoxidil 2% or 5 and antiandrogens (cyproterone acetate, spironolactone) when hyperandrogenism is manifest finasteride or dutasteride are not currently indicated but not finasteride is being evaluated in postmenopausal women.

15 thoughts on “The Causes Of Hair Loss?

  1. Bethany W

    why can some women control lupus and others cant?
    my mom suffered from lupus for 15 years and recently passed away last january. doctors say that lupus can be controlled through chemotherapy, she did every kind of treatment available for the disease and still could not fight it. but in other women with lupus can fight lupus with treatment why do you think some can fight it and others cant?

    1. Elvis4ever

      I think your mom did fight it – for 15 years . this is a very debilitating illness and it can be soul destroying with its multiple symptoms and the effect they can have on the mind as well as the body. I hope you can be comforted by the fact that she stayed with you so long and endured all those horrible treatments to keep her family close, it takes a lot of courage to go through chemo and I have the greatest respect for those that do it so they can have maximum time with their loved ones.
      I am sorry that you lost your mom, she is now with the angels and in no more pain. Bless you all

  2. Anonymous

    Will I ever be thin again?
    Okay, so I am 13 years old, and I have lupus of the brain, which also cause lesions to develop on my brain. I am on tons of medication, as well as I am being treated with chemotherapy once a month (jan will be my third treatment and im supposed to have either 5 or 7). Im puffy and overweight from all of the meds and chemo, but thankfully, I am weaning down on prednisone (corticosteroid) 10mg every four weeks or so, today I just cut back from 50mg to 40mg.
    I have been on pred since june 2010 at 30mg, then this past sepember i went shooting up to 60mg.
    Anyway, as I sid I am weaning off the pred, and hopefully I’ll be done my chemo at 5 treatments rather than 7.
    But, I am a teenaged girl, and Im fat and ugly, so you can imagine my biggest concern is of my weight, and the way I look.
    At what dose of prednisone will I start to lose my puffiness, and lose the weight.
    Also I will never be fully off prednisone either.
    And will I be THIN for my Grade 8 Graduation (June 2011) ?
    Inspiring and motivational answers only please!
    to AngryBunny,
    if you had nothing inspiring or motivational to say, then why did you say anything at all.

    1. Aragorn

      Dear young lady,
      Your first order of business is to get yourself healthy. Of course you will be slim again. The side effects of many of those powerful medications may be unpleasant, but they will pass completely as you no longer need them and stop using them. There will be time for you to do all of that, but your health must come first.
      I know it sucks that you’re dealing with this at your age, but it will pass. You’ll have time to be beautiful on the outside as well as inside. Try to be patient with your self and your treatment.

  3. Anonymous

    Do you still recieve Medical Benefits if you recieve a hardship discharge from the Army?
    I have severe systemic lupus erythematosus and it has put a huge hardship on my family. I have been getting treated for it but its getting really bad, so bad I have to be on Chemotherapy. We heard that my husband could possibly get discharged out of the army on a hardship discharge. Our only concern is that my treatment costs a lot and we’re not sure if we will still receive the medical coverage if he is discharged. Can anyone help???

  4. Anonymous

    Iritis, Uveitis, and Hodgkin’s Lymphoma?
    When i was pregnant with my daughter (who just turned 3) I got a small case of Iritis. I got it taken care of fairly fast and didn’t have any more problems with it until after I had my son (who will be 2 in Dec). It got to the point to where I almost lost my vision completely. I was on a steroid eye drop, a dilator eye drop and a steroid pill. Then at the end of last year I had these random bumps appear on my right calf. I went to some family doctors in my area and they all just tested for Lupus and every time it came back negative, so finally I went to a rheumatologist and she wanted to get some lymph nods in my neck biopsied and even to try to get the bumps in my legs biopsied. They surgeon said he didn’t think it was cancer and he couldn’t do anything about my bumps on my leg or at least biopsied but he did do the ones in neck and just 4 days after my surgery he told me that it was cancer. So since March I have been under going chemotherapy for Stage 4 Hodgkin’s Lymphoma and I only have 1 more treatment left. My eyes still aren’t any better and I think that my cancer is gone but who really know until a doctor tells you that u are cured.
    I was wondering if anyone could help me with any of this or if anyone has gone through any of what I am going through.

  5. Jessica

    Can anyone give me any advice on Rituximab / Rituxan?
    I am 20 years old, I have been diagnosed with Lupus (SLE) for seven years now. I have been on a variety of medication including prednisone, cellcept, plaquanil, immuran, and even cytoxan which is another iv chemotherapy type medication. After my last treatment of cytoxan I had been on remission for a little over a year, just to find out a month ago that I am going through a flare again. My doctor wants to start me on Rituximab/Rituxan because he believes that is the only way to stop my flare since the other medications do not seem to be working. After going through cytoxan I am actually really scared on being put on another iv treatment, the effects were horrendous and just by thinking about it makes me sick to my stomach. I have heard the effects of Rituximab/Rituxan are not as bad however I would appreciate if anyone can give me feedback if you have been on this medication or know someone that has, is it really bad? I am coming to the end of the semester, I am currently a junior in university, my gpa is rather great and I would not like this to affect my school activities. Therefore I would like to know how Rituximab or Rituxan affects everyday life when given to you. Thank you so much for your help in advance and I hope someone is able to help me, I am truly going to appreciate it!

    1. Linda R

      I have SLE and I also work with lupus patients. Rituxan is a chemotherapy that was designed to treat non-Hodgkins lymphoma. It has also proven useful in treating lupus that does not respond well to the therapies you already tried. I personally know 3 patients who have taken Rituxan. They do report some of the side effects that you read about. One of them was my teaching partner for a 6 week workshop. She did manage to teach throughout that time, but fatigue was certainly an issue. However, it’s hard to tell if the fatigue was from the Rituxan or the lupus itself.

      Ask your rheumatologist if he/she has other patients who would be willing to sit down and share their experiences with you. Also realize that just as lupus affects each one of us differently, so do the medications. Best of luck to you!

  6. Anonymous

    What is Lupus? Is it Terminal?
    I found out today that my grandmother ( 80 years old ) has lupus. I’m not sure what it really is. Will she die from this? My mom said something about treatment for it.. is that similar to chemotherapy in the way that it will make her sick?

    1. Rita V

      Lupus, I have had Lupus since 1990 and it’s basically like being allergic to your own body, the white cell that run to fight infection they attack the good bacteria like it was a bad cold of anything Thrre 2 typed of Lupus= first Discoid involves bascily its refering to the skin only about everyone with discoid Lupus they have a skin problens, a rash that srart crossing the nose and cross the cheeks they call this a butterd Fly rash. I will give you a wed site that will give more you information. the w is WEB MD the information on there is incredible. Good Luck Rita V

  7. sekhmet179

    What are the four stages of treatment for lupus?
    I remember reading somewhere that there were four stages of treatment for systemic lupus erythematosus I think it was like
    IV-Immunosuppressors, chemotherapy, etc

    I was wondering if there was anything like this on the internet or whether I am confusing it with the kidney affected stages? (I doubt it but you never know…)

    Thanks in advance for any info, and please be sure to set up a link to where you got your info

    1. Cheryl M

      What is the treatment for systemic lupus?

      There is no permanent cure for SLE. The goal of treatment is to relieve symptoms and protect organs by decreasing inflammation and/or the level of autoimmune activity in the body. Many patients with mild symptoms may need no treatment or only intermittent courses of antiinflammatory medications. Those with more serious illness involving damage to internal organ(s) may require high doses of corticosteroids in combination with other medications that suppress the body’s immune system.

      Patients with SLE need more rest during periods of active disease. Researchers have reported that poor sleep quality was a significant factor in developing fatigue in patients with SLE. These reports emphasize the importance for patients and physicians to address sleep quality and the effect of underlying depression, lack of exercise, and self-care coping strategies on overall health. During these periods, carefully prescribed exercise is still important to maintain muscle tone and range of motion in the joints.

      Nonsteroidal antiinflammatory drugs (NSAIDs) are helpful in reducing inflammation and pain in muscles, joints, and other tissues. Examples of NSAIDs include aspirin, ibuprofen (Motrin), naproxen (Naprosyn), and sulindac (Clinoril). Since the individual response to NSAIDs varies among patients, it is common for a doctor to try different NSAIDs to find the most effective one with the fewest side effects. The most common side effects are stomach upset, abdominal pain, ulcers, and even ulcer bleeding. NSAIDs are usually taken with food to reduce side effects. Sometimes, medications that prevent ulcers while taking NSAIDs, such as misoprostol (Cytotec), are given simultaneously.

      Corticosteroids are more potent than NSAIDs in reducing inflammation and restoring function when the disease is active. Corticosteroids are particularly helpful when internal organs are involved. Corticosteroids can be given by mouth, injected directly into the joints and other tissues, or administered intravenously. Unfortunately, corticosteroids have serious side effects when given in high doses over prolonged periods, and the doctor will try to monitor the activity of the disease in order to use the lowest doses that are safe. Side effects of corticosteroids include weight gain, thinning of the bones and skin, infection, diabetes, facial puffiness, cataracts, and death (necrosis) of large joints.

      Hydroxychloroquine (Plaquenil) is an antimalarial medication found to be particularly effective for SLE patients with fatigue, skin, and joint disease. Side effects include diarrhea, upset stomach, and eye pigment changes. Eye pigment changes are rare, but require monitoring by an ophthalmologist (eye specialist) during treatment with Plaquenil. Researchers have found that Plaquenil significantly decreased the frequency of abnormal blood clots in patients with systemic SLE. Moreover, the effect seemed independent of immune suppression, implying that Plaquenil can directly act to prevent the blood clots. This fascinating work highlights an important reason for patients and doctors to consider Plaquenil, especially for those SLE patients who are at some risk for blood clots in veins and arteries, such as those with phospholipid antibodies (cardiolipin antibodies, lupus anticoagulant, and false positive VDRL). This means not only that Plaquenil reduces the chance for reflares of SLE, but it can also be beneficial in ‘thinning’ the blood to prevent abnormal excessive blood clotting.

      For resistant skin disease, other antimalarial drugs, such as chloroquine (Aralen) or quinacrine, are considered, and can be used in combination with hydroxychloroquine. Alternative medications for skin disease include dapsone and retinoic acid (Retin-A). Retin-A is often effective for an uncommon wart-like form of lupus skin disease. For more severe skin disease, immunosuppressive medications are considered as below.

      Medications that suppress immunity (immunosuppressive medications) are also called cytotoxic drugs. Immunosuppressive medications are used for treating patients with more severe manifestations of SLE with damage to internal organ(s). Examples of immunosuppressive medications include methotrexate (Rheumatrex, Trexall), azathioprine (Imuran), cyclophosphamide (Cytoxan), chlorambucil (Leukeran), and cyclosporine (Sandimmune). All immunosuppressive medications can seriously depress blood cell counts and increase risks of infection and bleeding. Other side effects are peculiar for each drug. For examples, Rheumatrex can cause liver toxicity, while Sandimmune can impair kidney function.

      In recent years, mycophenolate mofetil (Cellcept) has been used as an effective medication for lupus, particularly when it associated with kidney disease. Cellcept has been helpful in reversing active lupus kidney disease (lupus renal disease) and in maintaining remission after it is established. It’s lower side effect profile has advantage over traditional immune suppression medications.

      In SLE patients with serious brain or kidney disease, plasmapheresis is sometimes used to remove antibodies and other immune substances from the blood to suppress immunity. Some SLE patients can develop seriously low platelet levels, thereby increasing the risk of excessive and spontaneous bleeding. Since the spleen is believed to be the major site of platelet destruction, surgical removal of the spleen is sometimes performed to improve platelet levels. Other treatments have included plasmapheresis and the use of male hormones. Plasmapheresis has also been used to remove proteins (cryoglobulins) that can lead to vasculitis. Endstage kidney damage from SLE requires dialysis and/or a kidney transplant.

      Most recent research is indicating benefits of rituximab (Rituxan) in treating lupus. Rituximab is an intravenously infused antibody that suppresses a particular white blood cell, the B cell, by decreasing their number in the circulation. B cells have been found to play a central role in lupus activity, and when they are suppressed, the disease tends toward remission.

      At the 2007 national Rheumatology meeting, there was a paper presented suggesting that low dose dietary supplementation with omega-3 fish oils could help patients with lupus by decreasing disease activity and possibly decreasing heart disease risk.

  8. Carol N

    Can anyone tel me the latest treatment for lupus [ S L E ]?
    My daughter has just finnished a course of chemotherapy as her kidneys are the latest organ to be attacked

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